Table 3.
Effects of nicotiflorin on the body weight and the liver and speen indexes in d-GalN-intoxicated mice.
Group | Inital BW (g) | Final BW (g) | Liver Index | Speen Index |
---|---|---|---|---|
Control | 20.72 ± 0.59 | 25.02 ± 1.11 | 45.12 ± 1.13 | 4.25 ± 0.22 |
d-GalN | 20.28 ± 0.34 | 26.35 ± 0.72 | 84.44 ± 1.47 ## | 8.26 ± 0.20 ## |
DDB (150 mg/kg bw) + d-GalN | 21.36 ± 0.42 | 26.38 ± 0.58 | 53.75 ± 1.09 ** | 5.54 ± 0.18 ** |
nicotiflorin (25 mg/kg bw) + d-GalN | 21.25 ± 0.48 | 25.64 ± 0.46 | 65.44 ± 0.89 ** | 6.43 ± 0.57 ** |
nicotiflorin (50 mg/kg bw) + d-GalN | 21.26 ± 0.59 | 26.13 ± 0.80 | 57.48 ± 2.46 ** | 5.55 ± 0.30 ** |
nicotiflorin (100 mg/kg bw) + d-GalN | 20.71 ± 0.59 | 26.75 ± 0.56 | 49.35 ± 1.50 ** | 4.88 ± 0.23 ** |
Values are mean ± S.E.M., n = 10. ## p < 0.01 compared with the control group. ** p < 0.01 compared with the Con A group. BW, body weight.