Table 4.
Effects of nicotiflorin on the pathological grading of d-GalN-intoxicated mice.
Group | 0 | I | II | III | p-Value |
---|---|---|---|---|---|
Control | 10 | 0 | 0 | 0 | - |
d-GalN | 0 | 0 | 3 | 7 | # |
DDB (150 mg/kg bw) + d-GalN | 1 | 6 | 2 | 1 | * |
nicotiflorin (25 mg/kg bw) + d-GalN | 1 | 5 | 3 | 1 | * |
nicotiflorin (50 mg/kg bw) + d-GalN | 2 | 4 | 3 | 1 | * |
nicotiflorin (100 mg/kg bw) + d-GalN | 3 | 5 | 1 | 1 | * |
n = 10; # p < 0.01 compared with control group; * p < 0.05, compared with d-GalN group.