AD	Alzheimer’s disease
Aβ	Amyloid-β
AdipoR	Adiponectin receptor
AMPK	5′ adenosine monophosphate-activated protein kinase
APN	Adiponectin
APP	Amyloid precursor protein
APPL1	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
BACE1	β-site APP cleaving enzyme 1
BBB	Blood-brain barrier
CNS	Central nervous system
ERK1/2	Extracellular signal-regulated kinase1/2
FAD	Familial Alzheimer’s disease
GSK	Glycogen synthase kinase
HMW	High molecular weight
ICV	Intracerebroventricular
IV	Intravenous
IDE	Insulin degrading enzyme
IL1β	Interleukin 1β
IR	Insulin receptor
IRS-1	Insulin receptor substrate 1
JNK	c-Jun N-terminal kinase
LMW	Low molecular weight
LPS	Lipopolysaccharide
MAPK	Mitogen-activated protein kinases
MCI	Mild cognitive impairment
NFT	Neurofibrillary tangles
mTOR	mammalian target of rapamycin
NF-κB	Nuclear factor κ B
PPARα	Peroxisome proliferator-activated receptor α
PPARγ	Peroxisome proliferator-activated receptor γ
PS	Presenilin
SIRT-1	NAD-dependent deacetylase sirtuin-1
T2DM	Type 2 diabetes mellitus
TLR4	Toll-like receptor 4
TNFα	Tumor necrosis factor α