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. 2017 Mar 8;18(3):594. doi: 10.3390/ijms18030594

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) Schematic diagram of ferrimagnetic iron oxide nanocube (FION)-loaded chitosan nanoparticles for hyperthermia of cancer cells; (B) TEM images and physicochemical characterizations of FION-loaded chitosan nanoparticles: (a,b) TEM images of FION-loaded chitosan nanoparticles (red arrow indicates the chitosan polymer coating layers); (c) hydrodynamic diameters of FION-loaded chitosan nanoparticles in phosphate-buffered saline; (d) magnetization curves of FION-loaded chitosan nanoparticles and Feridex^® (Adapted with permission from [82]. Copyright 2012 American Chemical Society).