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Correlation between TC50 (Toxic Concentration, 50%) of zebrafish (X-axis) and LD50 (Lethal Dose, 50%) of mice (Y-axis). The analysis included seven of the nine tested methylxanthines: diprophylline was excluded because the value was too large and pentoxifylline because it was an outlier. Numbers linked to each dot correspond to a methylxanthine compound, as reported in Table 2.
