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. 2017 Mar 15;18(3):636. doi: 10.3390/ijms18030636

Figure 1.

Figure 1

The hairpin structure of pre-miR-146b and the sequence of mature miR-146b. The MIR146B gene is located in an intergenic region of chromosome 10q24.32 and transcribed into a precursor (pre-miR-146b) with 73 nucleotides in the nucleus, that is exported to the cytoplasm by Exportin-5 for additional processing to yield two mature microRNAs with 22 nucleotides, miR-146b-5p and miR-146b-3p. The sequence of mature miR-146b-5p and miR-146b-3p is colored in green and blue. The arrow shows the orientations from 5′ to 3′.