Table 3.
Demographics, viral types, and viral loads as independent factors predicting severity in infants with RSV infection.
| Severe RSV Infection | ||
|---|---|---|
| Independent factors | OR (95% CI) | p-Value |
| Male gender | 2.09 (0.87–5.02) | 0.1 |
| Age (days) | 1.00 (0.99–1.00) | 0.59 |
| RSV antigenic type | 1.10 (0.46–2.62) | 0.82 |
| RSV genotype a | ||
| GA2 | 1.07 (0.26–4.28) | 0.93 |
| ON | 1.07 (0.38–3.06) | 0.89 |
| BA | 1.19 (0.50–2.80) | 0.68 |
| RSV genomic loads | ||
| All cases (n = 86) | 1.26 (0.86–1.86) | 0.23 |
| Early disease b (n = 61) | 1.02 (0.65–1.63) | 0.90 |
| Late disease c (n = 25) | 2.51 (0.85–7.41) | 0.09 |
RSV, respiratory syncytial virus; OR: odds ratio; CI: confidence interval; ON: Ontario; BA: Buenos Aires; a Reference value = “other genotypes”; b Early disease: 3 days or less of lower respiratory symptoms; c Late disease: more than 3 days of lower respiratory symptoms.