Table 1.

Proteins changed which contribute to loss of protein quality control in ah.

Protein	Function	Reference
Uba6	FAT10ylation pathway	[1]
USE1	FAT10ylation pathway	[1]
Ufa1	Ufmylation pathway	[1]
Uba5	Ufmylation pathway	[1]
FAT10	FAT10ylation pathway	[2,3]
Ubiquitin	26S proteasome pathway	[4]
LMP7	Immunoproteasome pathway	[5]
DNMT1	DNA methylation	[7]
DNMT3B	DNA methylation	[7]
Mca1	Chaperones pathway	[9]
Hsp104	Autophagia pathway	[9]
p62	Autophagia pathway	[10]
Hsp70/Hsp4	Autophagia pathway	[10]
Ydjl/SSa1	ERAD pathway	[11]
VCP/97	26S proteasome pathway	[12]
JUNQ	Protein sequestration	[13]
IPOD	Protein sequestration	[13]
ATG 1-10	Autophagy pathway	[15]
TORC1	Inhibits autophagy	[16]
ULK1	Inhibits autophagy	[16]
AMPK	Activates autophagia	[16]
mTOR	Inhibits autophagia	[20]
PERK	Inhibits ER stress	[26]
CHOP IL-1B	Apoptosis, inflammasome, cell cycle arrest	[31]
ATM	Inhibit liver regeneration	[32]
p21	Inhibit liver regeneration	[32]
p27	Inhibit liver regeneration	[32]
p15	Inhibit liver regeneration	[32]
TGFβ	Inhibit liver regeneration	[32]