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Inhibition of c9orf72 antisense foci by ss-siRNAs. (A) List of ss-siRNAs that are complementary to the expanded CCCCGG repeat and controls. (B) Quantitation of microscopy showing the percentage of cells with RNA foci and the number of foci per 100 cells. ss-siRNAs were transfected into patient-derived fibroblast cells with lipid RNAiMAX (Life Technologies) as previously described [19].
