Figure 1.

Selective antimicrobial activity of chemerin peptide p4 against oral bacteria. Chemically synthesized chemerin p4 and scramble p4 (scp4) peptides as well as LL37 were tested against the indicated oral cavity bacterial strains using MDA assay. Bacteria were incubated with p4 and scp4 at 100 µM, and LL37 at 11 µM for 3 h. The results are expressed as the mean ± SD of three independent experiments. ***p < 0.001, **p < 0.01, *p < 0.05 by Kruskal–Wallis one-way ANOVA with post Dunn’s test for multiple comparison, comparing vehicle treated bacteria (control) and the peptide-treated bacteria, or p4 vs. scp4.