Table 3.
Muscle weights and grip force in immobilized Wistar rats.
| 7 DAYS | 14 DAYS | 28 DAYS | ANOVA | ||||||
|---|---|---|---|---|---|---|---|---|---|
| CONTROL | IMMO | CONTROL | IMMO | CONTROL | IMMO | I | T | IXT | |
| GSN | 597.6 ± 16.1(5) | 604.1 ± 8.2(6) | 592.2 ± 14.7(9) | 607.7 ± 9.7(12) | 674.4 ± 8.0(5) | 659.0 ± 16.6(6) | ns | 0.001 | ns |
| EDL | 47.1 ± 2.0(5) | 48.4 ± 1.3(6) | 45.6 ± 1.3(9) | 47.2 ± 0.7(12) | 49.2 ± 0.3(5) | 48.6 ± 1.9(6) | ns | ns | ns |
| TIB | 184.6 ± 10.2(5) | 193.6 ± 2.3(6) | 194.0 ± 5.1(9) | 195.9 ± 3.1(12) | 207.4 ± 5.7(5) | 207.5 ± 6.3(6) | ns | 0.012 | ns |
| SOL | 43.7 ± 2.9(5) | 40.5 ± 0.9(6) | 42.7 ± 1.5(8) | 38.2 ± 0.5(12) | 48.2 ± 2.1(5) | 41.8 ± 0.6(6) | 0.001 | 0.004 | ns |
| HEART | 264.8 ± 7.8(5)b | 244.3 ± 3.0(6)a | 276.3 ± 3.8(9)b | 240.9 ± 7.2(12)a | 266.7 ± 5.5(5)b | 269.3 ± 7.7(6)b | 0.004 | ns | 0.026 |
| GRIP FORCE | 3.8 ± 0.1(5) | 3.3 ± 0.1(6) | 3.7 ± 0.1(8) | 3.5 ± 0.1(11) | 4.0 ± 0.2(5) | 3.8 ± 0.2(6) | 0.005 | 0.029 | ns |
Mean ± SEM for the number of animals indicated in parentheses are shown for every period for control (CONTROL) and immobilized (IMMO) groups. Muscle weights are expressed as milligrams per 100 grams of initial body weight. Statistical significance was tested by a full factorial two-way ANOVA (fixed factors: I, immobilization, T, Time; IxT denotes the interaction term), p-values are shown in the three columns on the right (ns, non-significant differences, which implies a p-value equal to or greater than 0.05). It has been detected a significant interaction term in the model for the heart, so that pairwise comparisons were performed (Duncan method); different letters indicate significant differences between the experimental groups. GSN, gastrocnemius, EDL, extensor digitorum longus, TIB, tibialis, SOL: soleus. Muscle force of the animal was tested once a week and was expressed as g/g initial body weight.