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. 2017 Mar 29;9:73. doi: 10.3389/fnagi.2017.00073

Table 2.

Highly ranked genes identified in meta-analysis.

Gene symbol Gene name Overall gene score
SNCA Synuclein, alpha (non A4 component of amyloid precursor) 198.65
HBD Hemoglobin, delta 198.05
VNN2 Vanin 2 197.47
LILRA5 Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 196.91
EPB42 Erythrocyte membrane protein band 4.2 194.19
MARCH8 Membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 193.09
DUSP6 Dual specificity phosphatase 6 190.62
RIOK3 RIO kinase 3 (yeast) 185.68
FOS FBJ murine osteosarcoma viral oncogene homolog 176.01
FOSB FBJ murine osteosarcoma viral oncogene homolog B 165.59
DUSP1 Dual specificity phosphatase 1 164.85
APBA2 Amyloid beta (A4) precursor protein-binding, family A, member 2 163.30
TCEA1 Transcription elongation factor A (SII), 1 159.45
OASL 2′-5′-oligoadenylate synthetase-like 157.68
XAF1 XIAP associated factor 1 156.96
SLC11A2 Solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 152.44
CA6 Carbonic anhydrase VI 151.13
LTBP3 Latent transforming growth factor beta binding protein 3 146.04
SNRNP70 Small nuclear ribonucleoprotein 70 kDa (U1) 142.52
LETM1 Leucine zipper-EF-hand containing transmembrane protein 1 138.23
NAMPT Nicotinamide phosphoribosyltransferase 134.16
SSRP1 Structure specific recognition protein 1 127.97
TMEM19 Transmembrane protein 19 127.97
RPA4 Replication protein A4, 30 kDa 127.13
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 99.91

Top 24 genes identified in meta-analysis. These genes were differentially expressed in at least two out of the four studies. The overall gene score is calculated from a non-parametric ranking in NextBio.