Table 1.
Clinical data and characteristics of the diabetic status by maternal vitamin C (vitC) within the last four weeks of pregnancy (n = 23/24) and of the whole cohort (n = 47).
| VitC > Median >26.6 μmol/L | VitC ≤ Median ≤26.6 μmol/L | p Value | Characteristics of the Whole Cohort | |
|---|---|---|---|---|
| Vit C (μmol/L), n = 23/24/47 | 37.1 (28.2–61.0) 1 | 22.1 (3.1–28.2) | 30.1 (13.6) | |
| Age (yr), n = 23/24/47 | 28.8 (3.7) 2 | 27.7 (3.5) | 0.314 | 27 (26–31) |
| Maternal weight at delivery (kg) n = 12/11/23 | 78.5 (72.3–87.5) | 74.0 (68.0–86.0) | 0.32 | 78 (70–86) |
| Maternal height (cm), n = 11/11/22 | 166.2 (6.2) | 164.4 (8.3) | 0.569 | 165.3 (7.2) |
| Diabetes duration (year), n = 23/24/47 | 15.0 (8.9) | 13.2 (9.0) | 0.486 | 14.1 (8.9) |
| Parity, n = 23/24/47 | 1.8 (0.8) | 1.8 (0.7) | 0.876 | 2 (1.2) |
| Systolic blood pressure at entry (mmHg), n = 15/14/29 | 120.1 (10.3) | 120.5 (9.9) | 0.641 | 120.0 (9.9) |
| Diastolic blood pressure at entry (mmHg) n = 15/14/29 | 72.1 (6.6) | 70.9 (6.7) | 0.673 | 71.2 (6.9) |
| Retinopathy Non/Simplex/Proliferative, n = N/S/P | 12/8/3 | 12/9/3 | 0.881 | 24/17/6 |
| BMI (kg/m2) at delivery, n = 11/10/21 | 29.2 (3.8) | 27.6 (4.4) | 0.607 | 28.6 (4.3) |
| Normo-/Micro-/Macro-albuminuria n = N/Mi/Ma | 18/4/1 | 20/4/0 | 0.581 | 38/8/1 |
| HbA1c (%) at entry, n = 22/23/45 | 7.7 (1.6) | 7.9 (1.2) | 0.0697 | 7.7 (1.4) |
| Creatinine clearance at entry (ml/min) n = 15/15/30 | 123.3 (22.1) | 116.2 (32.3) | 0.869 | 122.1 (27.1) |
| Smoking, n = Yes/no/unknown | 6/16/1 | 10/14/0 | 0.538 | 16/30/1 |
1 VitC levels in each subgroup is reported given as median (range); 2 Other data are listed as mean (SD), median (25%–75%) or n-values.