Table 4.
CG | MG | PIG | BG | BPG | BPIG | BPPIG | |
---|---|---|---|---|---|---|---|
Body weight (g) | 368.2 ± 32.7 | 397.4 ± 36.6 | 410.4 ± 47.5 | 390.3 ± 32.6 | 384.8 ± 28.9 | 394.7 ± 36.8 | 388.4 ± 33.2 |
Liver index (%) | 2.6 ± 0.3 | 3.2 ± 0.4 | 3.4 ± 0.5 | 3.0 ± 0.3 | 2.8 ± 0.3 | 3.1 ± 0.3 | 2.9 ± 0.3 |
epididymal fat weight (g) | 8.4 ± 1.3 | 9.8 ± 1.6 | 11.2 ± 1.8 | 9.1 ± 1.6 | 8.8 ± 1.3 | 9.3 ± 1.4 | 8.9 ± 1.5 |
Note: Liver index was presented as liver weight/body weight × 100%. All rat NASH models were evenly and randomly assigned to 6 groups: model group (MG, the model rats were intraperitoneally injected with 50 μL/kg saline solution and orally received 20 mL/kg liquid placebo daily); blueberry juice group (BG, the model rats were intraperitoneally injected with 50 μL/kg saline solution and orally received 10 mL/kg blueberry juice and 10 mL/kg liquid placebo daily); Blueberry juice and probiotic bacteria group (BPG, the model rats were intraperitoneally injected with 50 μL/kg normal saline solution and orally received 10 mL/kg blueberry juice and 10 mL/kg probiotics daily); PPAR-α inhibitor group (PIG, the model rats were intraperitoneally injected with 50 μL/kg PPAR-α in saline solution); blueberry juice and PPAR-α inhibitor group (BPIG, the model rats were intraperitoneally injected with 50 μL/kg PPAR-α in saline solution and orally received 10 mL/kg blueberry juice and 10 mL/kg liquid placebo daily); and blueberry juice, probiotics, and PPAR-α inhibitor group (BPPIG, the model rats were intraperitoneally injected with 50 μL/kg PPAR-α in saline solution and orally received 10 mL/kg blueberry juice and 10 mL/kg probiotics daily). Meanwhile, 8 healthy rats were used as a control group (CG, the healthy rats were intraperitoneally injected with 50 μL/kg normal saline solution and orally received 20 mL/kg liquid placebo daily).