Table 1.
SNP | CHR | Position | Locus | Gene Symbol | Location | MA | MAF | RAF | OR 1 | STAT | p |
---|---|---|---|---|---|---|---|---|---|---|---|
rs10924160 | 1 | 243519469 | 1q44 | KIF26B | intron | C | 0.345 | 0.345 | 1.180 | 4.146 | 3.39 × 10−5 |
rs7554672 | 1 | 219339781 | 1q41 | LOC101929750 | intron | A | 0.411 | 0.589 | 0.826 | −4.799 | 1.60 × 10−6 |
rs7419838 | 2 | 38894349 | 2p22.1 | DHX57 | intron | A | 0.117 | 0.883 | 0.766 | −4.160 | 3.19 × 10−5 |
rs1997377 | 2 | 38805170 | 2P22.1 | GALM | intron | T | 0.111 | 0.889 | 0.750 | −4.316 | 1.59 × 10−5 |
rs1562855 | 2 | 38861972 | 2p22.1 | GEMIN6 | intron | C | 0.142 | 0.858 | 0.781 | −4.314 | 1.60 × 10−5 |
rs11917719 | 3 | 24186676 | 3p24.2 | THRB | intron | T | 0.157 | 0.843 | 0.796 | −4.082 | 4.47 × 10−5 |
rs513130 | 5 | 72456095 | 5q13.2 | TMEM171 | intron | T | 0.405 | 0.595 | 0.838 | −4.334 | 1.46 × 10−5 |
rs6457792 | 6 | 34872421 | 6p21.31 | UHRF1BP1 | intron | G | 0.097 | 0.097 | 1.305 | 4.293 | 1.76 × 10−5 |
rs10260451 | 7 | 142918347 | 7q35 | EPHA1-AS1 | intron | A | 0.177 | 0.823 | 0.799 | −4.070 | 4.70 × 10−5 |
rs1643270 | 7 | 130826034 | 7q32.3 | MKLN1 | intron | C | 0.479 | 0.479 | 1.197 | 4.569 | 4.90 × 10−6 |
rs3800688 | 7 | 130843015 | 7q32.3 | PODXL | intron | G | 0.419 | 0.419 | 1.197 | 4.600 | 4.23 × 10−6 |
rs16927774 | 8 | 62771785 | 8q12.3 | ASPH | Intron | C | 0.213 | 0.787 | 0.820 | −4.091 | 4.30 × 10−5 |
rs911782 | 10 | 123996033 | 10q26.13 | TACC2 | intron | T | 0.141 | 0.141 | 1.242 | 4.067 | 4.75 × 10−5 |
rs10466739 | 11 | 78290369 | 11q14.1 | TENM4 | intron | C | 0.198 | 0.198 | 1.221 | 4.286 | 1.82 × 10−5 |
rs11105368 | 12 | 88598572 | 12q21.33 | ATP2B1 | Intron | C | 0.376 | 0.624 | 0.810 | −5.247 | 1.55 × 10−7 |
rs1378942 | 15 | 72864420 | 15q24.1 | CSK | Intron | A | 0.172 | 0.828 | 0.793 | −4.380 | 1.19 × 10−5 |
rs3784789 | 15 | 72869605 | 15q24.1 | CSK, MIR4513 | Intron, upstream | G | 0.169 | 0.831 | 0.799 | −4.167 | 3.08 × 10−5 |
rs11866964 | 16 | 48217182 | 16q12.1 | ZNF423 | intron | A | 0.231 | 0.769 | 0.826 | −4.102 | 4.10 × 10−5 |
rs1858821 | 22 | 30006454 | 22q12.2 | LIMK2 | downstream | T | 0.145 | 0.855 | 0.788 | −4.221 | 2.44 × 10−5 |
rs4141404 | 22 | 30005185 | 22q12.2 | LIMK2 | 3′ UTR | A | 0.145 | 0.855 | 0.788 | −4.221 | 2.44 × 10−5 |
rs2040533 | 22 | 30009110 | 22q12.2 | PIK3IP1 | missense, 3′ UTR | G | 0.146 | 0.854 | 0.788 | −4.211 | 2.54 × 10−5 |
rs2413035 | 22 | 29930460 | 22q12.2 | RNF185 | intron | T | 0.149 | 0.851 | 0.791 | −4.075 | 4.61 × 10−5 |
SNP, single nucleotide polymorphism; CHR, chromosome; MA, minor allele; MAF, minor allele frequency; RAF, risk allele frequency; OR, odds ratio; STAT, test statistic; UTR, untranslated region. 1 Odds ratios and p-values were calculated in multivariable logistic regression models, which were adjusted for age, sex, body mass index (BMI), and recruitment area.