Table 6.

Significant interactions between gene polymorphisms and 24 h estimated urinary factors obtained with Kawasaki formula in sample 2.

	Urinary Factors
	T1	T2	T3	p-Interaction
24HUNa (mEq/day)
LOC101929750 (rs7554672)				0.028
AA	1.00 (ref.)	1.33 (0.77–2.29) 1	0.79 (0.44–1.43)
AG	1.33 (0.82–2.14)	1.25 (0.77–2.01)	1.92 (1.20–3.06)
GG (wild type)	1.75 (1.07–2.84)	2.04 (1.26–3.31)	2.16 (1.33–3.50)
24HUK (mEq/day)
LOC101929750 (rs7554672)				0.034
GG (wild type)	1.00 (ref.)	0.92 (0.67–1.27)	0.72 (0.52–1.01)
AG	0.65 (0.48–0.89)	0.58 (0.42–0.79)	0.74 (0.55–1.01)
AA	0.67 (0.44–1.03)	0.36 (0.22–0.58)	0.40 (0.26–0.62)
MKLN1 (rs1643270)				0.034
CC	1.00 (ref.)	1.55 (1.01–2.38)	1.22 (0.80–1.87)
CT	1.16 (0.79–1.70)	0.83 (0.56–1.22)	0.85 (0.58–1.26)
TT (wild type)	0.97 (0.63–1.48)	0.74 (0.48–1.14)	0.89 (0.58–1.38)
24HUNa-K Ratio
CSK (rs1378942)				0.012
AA	1.00 (ref.)	0.09 (0.01–0.83)	0.80 (0.23–2.75)
AC	0.67 (0.27–1.69)	0.94 (0.38–2.35)	0.73 (0.29–1.84)
CC (wild type)	0.93 (0.38–2.26)	0.99 (0.41–2.42)	1.25 (0.51–3.05)
CSK-MIR4513 (rs3784789)				0.026
GG	1.00 (ref.)	0.10 (0.01–0.89)	0.89 (0.26–3.09)
CG	0.66 (0.26–1.66)	0.91 (0.36–2.28)	0.74 (0.26–1.88)
CC (wild type)	0.92 (0.38–2.25)	0.99 (0.40–2.42)	1.22 (0.50–2.99)
TENM4 (rs10466739)				0.034
TT (wild type)	1.00 (ref.)	0.99 (0.77–1.26)	1.09 (0.85–1.40)
CT	0.86 (0.63–1.16)	1.06 (0.78–1.45)	1.43 (1.07–1.93)
CC	0.31 (0.11–0.93)	1.49 (0.78–2.85)	0.90 (0.43–1.87)

T, tertile; 24HUNa, 24 h urinary Na; 24HUK, 24 h urinary K; 24HUNa-K Ratio, 24 h urinary Na-K ratio. ¹ Odds ratio (95% Confidence intervals). All models were adjusted for age, sex, body mass index, energy intake, smoking status, regular exercise status, chronic disease prevalence status, recruitment area, and household income.