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. 2017 Mar 16;9(3):293. doi: 10.3390/nu9030293

Figure 4.

Figure 4

Effects of PM treatment on hepatic cholesterol homeostasis-related proteins in hypercholesterolemic rats. (A) Liver extracts from HCD diet, PM, and simvastatin treated groups were used for Western blot analysis; (B) Expression levels of SREBP1, FAS, and ACC were quantified by measuring band densities with National Institutes of Health (NIH) Image J software. β-actin was used as a loading control. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. # p < 0.05 vs. control group. * p < 0.05 vs. HCD-fed group. HCD, high cholesterol diet-fed group; low-, med-, and high-PM: low (1.65 × 109 cfu/kg/day), medium (5.5 × 109 cfu/kg/day), and high doses (1.65 × 1010 cfu/kg/day) of probiotic mixture-treated group, respectively; Sim, simvastatin-treated group.