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Reactivity of an Abasic Site at the Dyad Axis (AP73) in Various NCP Constructs
| kdis (10−6 s−1)a | t1/2 (h)a | Rel. Rate X : AP73 (11)b |
|
|---|---|---|---|
 |
3.80 ± 0.6 | 50.3 ± 8.7 | - |
 |
10.1 ± 0.3 | 19.0 ± 0.7 | 2.7 |
 |
12.7 ± 1.0 | 15.1 ± 1.2 | 3.4 |
Values presented are averages ± the standard deviation of at least three experiments each consisting of three replicates.
The relative rate equals the average rate constant for AP73 disappearance in a NCP containing a bistranded lesion/11.
