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Reactivity of a 2-Deoxyribonolactone Abasic Site at SHL 1.5 (L89) in Various NCP Constructs
| kdis (10−5 s−1)a | t1/2 (h)a | Rel. Rate X : L89 (14)b |
|
|---|---|---|---|
 |
1.58 ± 0.24 | 12.2 ± 2.1 | - |
 |
1.41 ± 0.07 | 13.6 ± 0.8 | 0.9 |
 |
2.41 ± 0.27 | 8.0 ± 1.0 | 1.5 |
Values presented are averages ± the standard deviation of at least three experiments each consisting of three replicates.
The relative rate equals the average rate constant for L89 disappearance in a NCP containing a bistranded lesion/14.
