Table 2.
MIC results for select compounds tested against nine strains of Staphylococcus aureus.
| MIC (μg/mL) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Compound | ATCC a | MW2 | JE2 | Newman | N315 | MC7606 b | MC7769 | MC7827 | MC7846 |
| 8973 | >128 c (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) |
| 5376 | 8 (4-8) | 4 (4) | 8 (8) | 4 (4) | 4 (2–4) | 2 (2) | 4 (4–8) | 8 (8) | 4 (4) |
| 5741518 | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) |
| 5870804 | 16 (16) | 32 (32) | 32 (32) | 64 (64) | 32 (32) | 4 (4) | 64 (64) | 32 (32–64) | 16 (16) |
| 2082-0182 | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) |
| 2083-1665 | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) |
| 2083-1773 | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) | >128 (>128) |
| Tetracycline | 0.25 (0.25–0.5) | 0.25 (0.25) | 0.25 (0.25) | 0.25 (0.25) | 0.25 (0.25) | 32 (16–32) | 0.25 (0.25) | 32 (32) | 0.125 (0.125) |
| Oxacillin | 0.25 (0.25) | 8 (8–16) | 8 (8–6) | 0.5 (0.5) | 16 (16) | 4 (4) | 4 (4) | 4 (4) | 4 (4–8) |
| Vancomycin | 0.5 (0.5) | 1 (1) | 1 (1) | 1 (1) | 1 (1) | 1 (1) | 1 (1) | 1 (1) | 4 (4) |
a ATCC is the American Type Culture Collection strain 29213; b Marshfield Clinic S. aureus clinical isolate; c The MICs represent the modal values (range) from at least three separate runs.