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. 2017 Mar 10;6(3):30. doi: 10.3390/jcm6030030

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© 2017 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Changes of the body weight in rats following administration of artemisinin and artesunate. (A) The groups administered artesunate; and (B) the groups administered artemisinin. The rats were divided into a normal group (n = 4) and experimental groups (n = 8/artesunate two groups, n = 8/artemisinin two groups, n = 4/each group). The rats were orally administered with two different doses (1.75 and 3.5 mg/kg) of artemisinin and artesunate, once a day for four weeks, respectively, and additionally observed for seven days. The results were expressed as a percentage of the normal group and presented as the mean ± S.D.