Table 2.
Minimum inhibitory concentration (MIC) values of artesunate and artemisinin against the growth of Mtb H37Rv for different incubation periods.
| Different Assays 1 | Incubation Days | MIC (µg/mL) of the Compounds against Mtb H37Rv Growth | |
|---|---|---|---|
| Artesunate | Artemisinin | ||
| REMA | 5 | 75 | 75 |
| MGIT 960 system | 21 | 300 | >600 |
| Ogawa slant medium | 21 | 300 | >600 |
1 The anti-Mtb activity/effect of the compounds was measured by the REMA, MGIT 960 system, and Ogawa slant medium assay. Mtb H37Rv was incubated with different concentrations (9.375–300 µg/mL) of the compounds at 37 °C, respectively, and their susceptibility was confirmed by different anti-Mtb–indicator assays. The results were carried out three times independently.