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. 2017 Mar 22;37(12):3425–3439. doi: 10.1523/JNEUROSCI.2752-16.2017

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Copyright © 2017 the authors 0270-6474/17/373425-15$15.00/0

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Figure 5. — Pathology induced by motor neuron HttQ138 expression. Expression of HttQ138 in motor neurons causes overgrowth similar to that observed after pan-neuronal expression. A, Representative images of muscle 4 NMJ overgrowth in Elav^C155;UAS-HttQ138-mRFP, C164-GAL4;UAS-HttQ138-mRFP, OK371;UAS-HttQ138-mRFP, Mef2-GAL4;UAS-HttQ138-mRFP, and Elav^C155;UAS-HttQ15-mRFP larvae. B, Quantification of satellite bouton number for each genotype. C, Quantification of the percentage of third-instar larval survival to adulthood for Elav^C155;UAS-HttQ138-mRFP, C164-GAL4;UAS-HttQ138-mRFP, OK371;UAS-HttQ138-mRFP, Mef2-GAL4;UAS-HttQ138-mRFP, Elav^C155;UAS-HttQ15-mRFP, MD-GAL4;UAS-HttQ138-mRFP, and OK107-GAL4;UAS-HttQ138-mRFP. ANOVA followed by Tukey's multiple-comparisons test was used for statistical analysis. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001. Error bars indicate SEM.