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Summary of associations between heritable thrombophilia and adverse pregnancy outcome.
| VTE | Early pregnancy loss | Recurrent first-trimester loss | Second-trimester loss | Late pregnancy loss | Pre-eclampsia | Placental abruption | FGR | |
|---|---|---|---|---|---|---|---|---|
| Factor V Leiden | ↑ | ↑ | ↑/←→ | ↑ | ↑ | ↑ | ↑ | ←→ |
| Prothrombin G20210A | ↑ | ↑ | ↑/←→ | ↑ | ↑ | ↑ | ↑ | ←→ |
| Protein C deficiency | ↑ | ←→ | ←→ | ←→ | ↑ | ←→ | ←→ | |
| Protein S deficiency | ↑ | ←→ | ←→ | ↑ | ←→ | ←→ | ←→ | |
| Antithrombin deficiency | ↑ | ←→ | ←→ | ←→ | ←→ | ←→ | ||
| Hyperhomocysteinemia | ←→ | ←→ | ←→ | ←→ | ↑ | ←→ | ←→ |
