Table 5.

The safety of LMWH in pregnancy.

Complication	Greer and Nelson-Piercy43 Systematic review Rate % (n = 2777)	Nelson-Piercy et al.44 Retrospective study Rate % (n = 1267)
VTE (overall)	0.86	1.19
VTE recurrence on treatment	1.15	1.97
Bleeding	Significant bleeding: 1.98 (1.50–2.57)	PPH > 500 = <1000 mL: 11
		PPH > 1000 = <1500 mL: 0.9
		PPH > 1500 mL:1.1
Wound haematoma	0.61	0.9
Heparin-induced thrombocytopenia	0.00	0
Osteoporosis	0.04	0.2

LMWH: low-molecular-weight heparin; VTE: venous thromboembolism; PPH: postpartum haemorrhage.