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. 2017 Mar 8;114(12):3192–3197. doi: 10.1073/pnas.1619588114

Fig. 3.

Fig. 3.

BAP1 inhibits UPR-mediated ROS induction and ATP depletion. (A) The effect of PERK inhibitor on glucose deprivation-induced apoptosis in UMRC6 stable cells. (B) The effect of PERK inhibitor on glucose deprivation-induced UPR effectors in UMRC6 stable cells. (C) The effect of reexpression of BAP1 and BAP1-C91A mutant on glucose deprivation-induced ROS in UMRC6 stable cells. (D) The effect of Bap1 deletion on glucose deprivation-induced ATP depletion in MEFs. **P < 0.01; ns, nonsignificant.