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. 2017 Mar 6;114(12):3151–3156. doi: 10.1073/pnas.1620262114

Fig. 1.

Fig. 1.

Survival of RosaPB/+;ATP2/+;Arf−/− mice and tumoral insertional landscapes. (A) Survival curve (conditional survival) showing significant acceleration of disease onset with activated PB transposon (P > 0.0001, log-rank test). (B) Number of masses harvested from necropsied animals is on average significantly higher for RosaPB/+;ATP2/+;Arf−/− mice than for ATP2/+;Arf−/− mice (P < 0.0001, Mann–Whitney U test). (C) Genetic landscape of PB insertions in the 327 RosaPB/+;ATP2/+;Arf−/− tumors sequenced.