Table 1.

Parameters for kinetic models

Rate constant	Gründer and Pusch	Gründer and Pusch fixed open/shut	Gründer and Pusch stoichiometric binding	Gründer and Pusch fit to data
kon	2 × 109	2 × 109	1 × 1010	1.4 × 108
koff	1,000	1,000	1,000	126
e	1.5	1.5	N/A	3.48
g	0.67	0.67	N/A	1.83
α	N/A	7.0 × 105	7.0 × 105	7.0 × 105
β	N/A	4.0 × 105	4.0 × 105	4.0 × 105
δ	2	2	2	2.49
γ	0.02	0.02	0.02	0.02

Rate constants used for simulations in Fig. 6 and Fig. S4. Values for unmodified Gründer and Pusch model (1st column) are taken from ref. 25. N/A, not applicable.