Table 2.
Differences in quality of life indicators within and between study groups
| Active Group | Control Group | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | 6 mo | Change (6 mo versus Baseline) | P Value (6 mo versus Baseline) | Baseline | 6 mo | Change (6 mo versus Baseline) | P Value (6 mo versus Baseline) | Changes Between Two Groups | P Value (Active versus Control) | |
| Kidney disease component | ||||||||||
| Symptom/problem list | 74.0 (70.3 to 77.6) | 73.4 (69.7 to 77.0) | −0.6 (from −3.1 to 1.8) | 0.62 | 73.4 (69.9 to 76.8) | 72.5 (69.0 to 76.0) | −0.8 (from −3.8 to 2.0) | 0.56 | −0.2 (from −3.9 to 3.5) | 0.91 |
| Effects of kidney disease | 57.6 (52.1 to 63.1) | 59.1 (54.1 to 64.1) | 1.5 (from −2.7 to 5.7) | 0.49 | 61.9 (57.7 to 66.1) | 61.6 (57.4 to 65.7) | −0.3 (from −4.0 to 3.4) | 0.86 | −1.8 (from −7.4 to 3.8) | 0.52 |
| Burden of kidney disease | 40.1 (33.8 to 46.4) | 42.7 (37.2 to 48.1) | 2.6 (from -2.2 to 7.3) | 0.28 | 41.6 (36.4 to 46.8) | 42.0 (36.5 to 47.4) | 0.4 (from −4.6 to 5.4) | 0.88 | −2.2 (from −9.0 to 4.7) | 0.53 |
| Work status | 29.3 (20.8 to 37.8) | 29.5 (21.0 to 38.1) | 0.3 (from −4 to 4.6) | 0.90 | 26.3 (19.3 to 33.3) | 25.4 (17.9 to 33.0) | −0.9 (from −6.5 to 4.7) | 0.75 | −1.2 (from −8.1 to 5.8) | 0.74 |
| Cognitive function | 68.7 (63.5 to 73.8) | 69.0 (64.1 to 73.8) | 0.3 (from −3.2 to 3.8) | 0.87 | 72.0 (66.8 to 77.2) | 65.6 (60.0 to 71.2) | −6.4 (from −11.9 to −0.9) | 0.02 | −6.7 (from −13.2 to −0.2) | 0.04 |
| Quality of social interaction | 76.8 (72.9 to 80.7) | 78.9 (75.7 to 82.1) | 2.1 (from −1.1 to 5.4) | 0.19 | 80.2 (76.4 to 84.0) | 75.6 (71.4 to 79.7) | −4.6 (from −8.3 to −0.9) | 0.02 | −6.7 (from −11.6 to −1.8) | 0.01 |
| Sexual function | 73.7 (65.6 to 81.8) | 68.8 (60.1 to 77.5) | −4.9 (from −12.6 to 2.7) | 0.20 | 66.3 (57.6 to 75.1) | 64.2 (55.5 to 72.9) | −2.1 (from −10.5 to 6.2) | 0.61 | 2.8 (from −8.4 to 14.0) | 0.62 |
| Sleep | 60.6 (56.6 to 64.6) | 64.2 (60.6 to 67.9) | 3.7 (from 0.8 to 6.6) | 0.01 | 58.3 (54.5 to 62.1) | 59.0 (55.4 to 62.5) | 0.7 (from −2.7 to 4.1) | 0.69 | −3.0 (from −7.4 to 1.4) | 0.19 |
| Social support | 72.4 (67.8 to 76.9) | 70.9 (65.8 to 75.9) | −1.5 (from −5.9 to 2.8) | 0.49 | 73.9 (69.6 to 78.1) | 71.9 (67.6 to 76.2) | −2.0 (from −6.2 to 2.3) | 0.36 | −0.5 (from −6.5 to 5.6) | 0.88 |
| Dialysis staff encouragement | 72.3 (69.5 to 75.1) | 71.3 (68.0 to 74.6) | 1.1 (from −4 to 1.9) | 0.48 | 75.4 (72.6 to 78.2) | 73.8 (71.0 to 76.6) | −1.6 (from −4.8 to 1.6) | 0.33 | −0.5 (from −4.9 to 3.8) | 0.80 |
| Patient satisfaction | 74.8 (69.7 to 79.9) | 73.2 (68.4 to 78.0) | −1.6 (from −5.1 to 2) | 0.39 | 75.9 (71.5 to 80.4) | 71.3 (66.7 to 75.9) | −4.6 (from −9.2 to −0.1) | 0.05 | −3.1 (from −8.8 to 2.7) | 0.29 |
| Physical functioning component | ||||||||||
| Physical functioning | 56.5 (49.7 to 63.3) | 57.9 (51.0 to 65.0) | 1.5 (from −2.7 to 5.6) | 0.49 | 55.5 (49.7 to 61.3) | 52.7 (46.4 to 59.0) | −2.7 (from −7.7 to 2.2) | 0.27 | −4.2 (from −10.6 to 2.2) | 0.20 |
| Role physical | 40.5 (30.9 to 50.2) | 40.8 (30.7 to 50.8) | 0.2 (from −9 to 9.5) | 0.96 | 41.7 (32.3 to 51.0) | 32.5 (23.7 to 41.3) | −9.2 (from −18.7 to 0.3) | 0.06 | −9.4 (from −22.6 to 3.8) | 0.16 |
| Pain | 57.9 (51.4 to 64.3) | 56.7 (50.7 to 62.7) | −1.1 (from −7.2 to 4.9) | 0.71 | 61.3 (54.7 to 67.9) | 58.1 (51.8 to 64.5) | −3.2 (from −9.3 to 2.9) | 0.30 | −2.0 (from −10.6 to 6.5) | 0.64 |
| General health | 35.7 (31.2 to 40.2) | 36.5 (31.8 to 41.1) | 0.8 (from −3 to 4.6) | 0.68 | 32.8 (29.1 to 36.4) | 30.3 (26.8 to 33.9) | −2.5 (from −6 to 1.1) | 0.17 | −3.2 (from −8.4 to 1.9) | 0.21 |
| Mental functioning component | ||||||||||
| Emotional wellbeing | 58.9 (53.7 to 64.2) | 60.1 (54.9 to 65.3) | 1.2 (from −2.6 to 5) | 0.53 | 62.9 (58.3 to 67.5) | 59.0 (54.2 to 63.7) | −3.9 (from −8.2 to 0.4) | 0.07 | −5.1 (from −10.79 to 0.6) | 0.08 |
| Role emotional | 54.9 (44.7 to 65.2) | 53.1 (42.9 to 63.4) | −1.8 (from -11.9 to 8.3) | 0.72 | 53.6 (44.4 to 62.9) | 46.2 (37.0 to 55.4) | −7.5 (from −17.6 to 2.7) | 0.15 | −5.7 (from −19.85 to 8.5) | 0.43 |
| Social function | 80.8 (75.4 to 86.1) | 78.3 (73.1 to 83.5) | −2.5 (from −8.2 to 3.3) | 0.40 | 80.0 (75.3 to 84.7) | 79.2 (74.2 to 84.2) | −0.8 (from −5 to 3.3) | 0.69 | 1.6 (from −5.44 to 8.7) | 0.65 |
| Energy/fatigue | 47.9 (42.2 to 53.0) | 47.1 (41.8 to 52.3) | 0.8 (from −5.1 to 3.4) | 0.70 | 49.8 (44.9 to 54.7) | 46.1 (41.0 to 51.1) | −3.7 (from −8.2 to 0.8) | 0.10 | −2.9 (from −9.0 to 3.3) | 0.35 |
| Total score | 62.3 (59.0 to 65.7) | 62.8 (59.5 to 66.2) | 0.5 (from −1.7 to 2.6) | 0.66 | 63.0 (59.9 to 66.0) | 61.2 (58.1 to 64.4) | −1.7 (from −4.1 to 0.6) | 0.15 | −2.2 (from −5.3 to 1.0) | 0.17 |
Data are mean and 95% CI.