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. 2017 Mar 30;12(3):e0174374. doi: 10.1371/journal.pone.0174374

Fig 3. UBC9 knockdown influences ECM expression.

Fig 3

(A) Representative images of 3 independent experiments with similar results are presented. Down-regulation of UBC9 reduced α-SMA and Collagen I protein. (B) Graph of the relative ratios of both α-SMA and Collagen I protein to β-actin in each group. *P < 0.05 compared with NC shRNA group, n = 4. (C) IL-6 and TNF-α concentrations in the supernatant of activated LX-2 cells was examined in the Normal, Lipo2000, shNC, and sh-UBC9 groups. #P <0.05 and*P < 0.001 compared with NC shRNA group, n = 4.