Table 2. Variables related to persistent/recurrent disease by age-and sex-adjusted binomial logistic regression analysis.

Variables	All PTCs (n = 512)			Classic PTCs (n = 451)
	HR	95% CI	p-value	HR	95% CI	p-value
Aggressive variant	3.187	1.013–10.032	0.048
pT (T1-2 vs. T3-4)	3.598	1.236–10.477	0.019	4.007	1.181–13.592	0.026
Lymph node metastasis	2.060	1.072–3.962	0.030	2.135	1.069–4.265	0.032
Lateral LN metastasis	4.535	2.266–9.076	< 0.001	4.468	2.095–9.525	< 0.001
Dyscohesive cells	2.461	1.003–6.035	0.049	2.438	0.914–6.506	0.075
Psammoma body	2.269	1.048–4.913	0.038	2.391	1.048–5.455	0.038
BRAF V600E mutation	0.929	0.365–2.364	0.877	0.678	0.260–1.769	0.427

Aggressive variants included 21 tall cell variant and 1 hobnail variant. Presence of dyscohesive cells in ≥ 1% of the tumor periphery and invasive front was categorized as positive. Presence of psammoma body was considered as positive when its number was more than 3. PTC, papillary thyroid carcinoma; LN, lymph node; HR, hazard ratio; CI, confidence interval.