Table 3. DWI characteristics of 141 lesions for predicting malignancy.
| Total | Benign | Malignant | p-value‡ | |
|---|---|---|---|---|
| Lesion size | ||||
| mean (SD) | 2.11±1.77 | 1.03±1.21 | 2.42±1.78 | <0.0001 |
| median(min-max) | 1.7 (0.3–10.2) | 0.75 (0.3–6.8) | 2.0 (0.5–10.2) | <0.0001 |
| ≤1 cm | 45 (31.5) | 25 (55.6) | 20 (44.4) | |
| >1 cm | 98 (68.5) | 7 (7.1) | 91 (92.9) | |
| Lesion type | <0.0001 | |||
| not seen | 3 (2.1) | 3 (100.0) | 0 (0.0) | |
| mass | 119 (82.6) | 22 (18.5) | 97 (81.5) | |
| nonmass | 22 (15.3) | 7 (31.8) | 15 (68.2) | |
| Shape (for mass) | <0.0001 | |||
| oval | 23 (19.3) | 12 (52.2) | 11 (47.8) | |
| round | 5 (4.2) | 1 (20.0) | 4 (80.0) | |
| irregular | 91 (76.5) | 10 (11.0) | 81 (89.0) | |
| Margin (for mass) | <0.0001 | |||
| circumscribed | 15 (12.6) | 9 (60.0) | 6 (40.0) | |
| irregular | 87 (73.1) | 14 (16.1) | 73 (83.9) | |
| spiculated | 17 (14.3) | 0 (0.0) | 17 (100.0) | |
| Distribution (for nonmass) | 0.0014 | |||
| focal | 10 (45.5) | 7 (70.0) | 3 (30.0) | |
| linear | 2 (9.0) | 0 (0.0) | 2 (100.0) | |
| segmental | 10 (45.5) | 0 (0.0) | 10 (100.0) | |
| Internal pattern (for both) | <0.0001 | |||
| homogenous | 39 (27.7) | 21 (53.9) | 18 (46.1) | |
| heterogenous | 77 (54.6) | 8 (10.4) | 69 (89.6) | |
| rim sign | 25 (17.7) | 0 (0.0) | 25 (100) | |
| ADC, ×10−3 mm2/s | <0.0001 | |||
| mean (sd) | 0.94±0.22 | 1.14±0.23 | 0.88±0.19 | |
| median (min-max) | 0.91(0.42–1.58) | 1.15(0.66–1.58) | 0.87(0.42–1.36) | |
| ADC, cutoff† | <0.0001 | |||
| <1.0×10-3mm2/s | 92 (65.25) | 6 (6.5) | 86 (93.5) | |
| ≥1.0×10-3mm2/s | 49 (34.75) | 23 (46.9) | 26 (53.1) |
Note_Values are presented as numbers (percentages) for categorical variables and mean (SD) and median (min-max) for continuous variables.
†The cutoff point determined by ROC curve with maximum Youden index.
‡P-values were calculated by using Chi-square test and Wilcoxon rank sum test.