Table 4. Univariate and multivariate logistic regression analysis of DWI characteristics for predicting malignancy.
| Lesion characteristics (for mass type) | No. of benign lesions (%) | No. of malignant lesions (%) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|---|
| Odds Ratio (95% CI) | p-value† | Odds Ratio (95% CI) | p-value‡ | |||
| Qualitative DWI analysis | 25 (20.7) | 96 (79.3) | ||||
| Shape | ||||||
| oval | 14 (53.9) | 12 (46.2) | 1 | 1 | ||
| round | 2 (33.3) | 4 (66.7) | 2.33 (0.36–15.05) | 0.373 | 1.33 (0.05–37.46) | 0.869 |
| irregular | 9 (10.1) | 80 (89.9) | 10.37 (3.69–29.16) | <0.0001 | 13.56 (0.64–289.51) | 0.095 |
| Margin | ||||||
| circumscribed | 13 (54.2) | 11 (45.8) | 1 | 1 | ||
| irregular | 12 (16.7) | 60 (83.3) | 5.91 (2.14–16.29) | 0.0006 | 0.32 (0.01–10.39) | 0.523 |
| spiculated | 0 (0) | 25 (100.0) | … | 0.942 | … | 0.966 |
| Internal pattern | ||||||
| homogenous | 19 (82.6) | 4 (17.4) | 1 | 1 | ||
| heterogenous | 6 (9.38) | 58 (90.6) | 45.92 (11.70–180.18) | <0.0001 | 21.34 (2.44–186.81) | 0.006 |
| rim sign | 0 (0) | 34 (100.0) | … | 0.926 | … | 0.947 |
| Quantitative DWI analysis | 22 (18.6) | 96 (81.4) | ||||
| ADC<1.0×10-3mm2/s | 5 (5.9) | 79 (94.1) | 15.80 (5.12–48.74) | <0.0001 | 19.07 (2.79–130.24) | 0.003 |
| ADC≥1.0×10-3mm2/s | 17 (50.0) | 17 (50.0) | 1 | |||
Note_ Lesion characteristics for NME type lesions were not included in the multivariate analysis because variables were not significant in the univariate analysis.
†Determined with the χ2 test.
‡Determined with logistic regression analysis.