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. Author manuscript; available in PMC: 2018 Mar 15.
Published in final edited form as: J Immunol. 2017 Feb 10;198(6):2244–2248. doi: 10.4049/jimmunol.1502266

FIGURE 3.

FIGURE 3

Sox2 dampens expression of the AID regulators Batf and Irf4. Cells were sorted based on mCherry expression as a marker of infection. (A) RNA-Seq was performed on samples from three independent infections. Differential expression of genes involved in CSR and in regulating AID expression (top) or genes expressed during B cell activation and differentiation (bottom) are shown. Genes shown below the arrow were not significantly different in the Sox2 expressing cells. (B, C) qPCR and immunoblot analysis of Irf4 and Batf expression levels in infected cells (n = 3).