Table 1.
Baseline characteristics and anthropometric measures of children with type 1 diabetes by race
| All subjects (n=600) | NHB (n=123) | NHW (n=477) | p-value* | |
|---|---|---|---|---|
| Age (years) at diagnosis* | ||||
| Mean (95% CI) | 7.9 (7.6,8.2) | 7.7 (7.1,8.4) | 7.9 (7.6,8.3) | 0.59 |
| Median (IQR) | 8 (5,11) | 8 (5,10) | 8 (5,11) | 0.49 |
| Age at Lipid profile | ||||
| Mean (95% CI) | 12.9 (12.7,13.2) | 13.0 (12.4,13.5) | 12.9 (12.7,13.2) | 0.90 |
| Median (IQR) | 13 (10,15) | 13 (10,15) | 13 (11,15) | 0.95 |
| Duration of diabetes at lipid profile | ||||
| Mean (95% CI) | 4.2 (3.9,4.5) | 4.4 (3.8,5.0) | 4.1 (3.8,4.5) | 0.49 |
| Median (IQR) | 3 (1,6) | 4 (1,6) | 3 (1,6) | 0.59 |
| Male (%) | 314 (52.3) | 59 (48.0%) | 255 (53.5%) | 0.31 |
| Mean Weight (kg) | 54.7±17.2 | 55.8 ± 15.4 | 54.5 ± 17.7 | 0.43 |
| Mean Height (cm) | 156.1±15.2 | 155.8 ± 13.5 | 156.2 ± 15.7 | 0.82 |
| Mean BMI (kg/m2) | 21.9±4.4 | 22.5 ± 4.1 | 21.7 ± 4.4 | 0.08 |
| BMI percentile | 69.6±25.5 | 74.7±70.5 | 68.3±66.0 | 0.0141 |
| Mean BMI z score | 0.0±1.0 | 0.12±0.95 | −0.03±1.00 | 0.12 |
| Mean Systolic blood pressure (mmHg) | 113.4±12.0 | 113.1 ± 12.8 | 113.4 ± 11.9 | 0.81 |
| Mean SBP z score | 0.0±1.0 | −0.04±1.00 | 0.01±0.98 | 0.59 |
| Mean Diastolic blood pressure (mmHg) | 64.2±7.9 | 64.6 ± 8.1 | 64.1 ± 7.9 | 0.51 |
| Mean DBP z score | 0.0±1.0 | 0.05±0.94 | −0.01±1.00 | 0.57 |
| Mean TC (mg/dl) | 174.6±37.6 | 186.5 ± 42.0 | 171.5 ± 35.8 | <0.0001 |
| Mean LDL-cholesterol (mg/dl) | 97.3±30.7 | 104.3 ± 37.3 | 95.6 ± 28.5 | 0.0049 |
| Mean HDL-cholesterol (mg/dl) | 57.1±13.8 | 63.7 ± 13.1 | 55.4 ± 13.5 | <0.0001 |
| Mean Triglycerides (mg/dl) | 122.3±105.5 | 118.5±112.4 | 123.2±103.8 | 0.6571 |
| VLDL (mg/dl) | 19.9±12.1 | 18.4±7.7 | 20.3±12.9 | 0.0438 |
| Mean Non-HDL (mg/dl) | 117.5±36.4 | 122.7 ± 40.5 | 116.2 ± 35.2 | 0.07 |
| Mean HDL/TC Ratio | 0.4±0.9 | 0.35 ± 0.1 | 0.38 ± 1.1 | 0.78 |
| Mean ApoB 100 (mg/dl) | 81.9±20.7 | 85.6 ± 24.6 | 80.9 ± 19.5 | 0.03 |
| Mean Lp(a) (mg/dl) | 9.4±5.7 | 11.2 ± 6.5 | 9.0 ± 5.4 | 0.0002 |
| Mean HDL 2 (mg/dl) | 15.7±6.5 | 18.9 ± 7.1 | 14.9 ± 6.0 | <0.0001 |
| Mean HDL 3 (mg/dl) | 41.4±8.3 | 44.7 ± 7.5 | 40.5 ± 8.2 | <0.0001 |
| LDL pattern (%) | ||||
| A | 344 (57.3) | 66 (53.7%) | 278 (58.3%) | 0.60 |
| A/B | 166 (27.7) | 36 (29.3%) | 130 (27.3%) | |
| B | 69 (15.0) | 21 (17.1%) | 69 (14.5%) | |
| Mean HbA1c (%) | 8..8±1.6 | 9.8 ± 2.2 | 8.6 ± 1.4 | <0.0001 |
*
Estimated from t-test or Wilcoxon rank sums test for means and medians, respectively, or chi-square test for categorical variables
†
NHB: non-Hispanic blacks; NHW: non-Hispanic whites; TC: total cholesterol; LDL: low density lipoprotein cholesterol; HDL: high density lipoprotein cholesterol
‡
Data are presented as frequency or mean ±SD