Figure 7. Entorhinal input drives CA1 deep layer neurons cells during early exploration of a familiar environment.
(A) Firing rate and theta-phase firing probability distribution (B) changes from early (trials 1–4) to late (mean of entire session) trials. Arrow indicates bump in the firing probability at the theta peak for deep CA1 cells in early trials. (C) Differences in range, onset, slope and strength of phase-position correlation for deep and superficial CA1 place cells. (D) Changes in spike-LFP phase coupling from early to late trials. Spike-gamma phase coupling was quantified for each neuron as a mean vector length ratio of the first 4 trials and the whole session, and averaged across the population. (*/**/*** p < 0.05/0.01/0.001, Wilcoxon signed-rank test for within-group and rank-sum test for across-group comparisons).