Table 1.
Demographic and clinical characteristics of the sample
| Characteristic | Group; no. (%) or mean ± SD [range] | |
|---|---|---|
|
| ||
| BD, n = 118 | Control, n = 86 | |
| Scan site | ||
| Centre 1 | 24 (20.5) | 22 (25.6) |
| Centre 2 | 53 (45.3) | 26 (30.2) |
| Centre 3 | 40 (34.2) | 38 (44.2) |
| Male sex | 47 (40.2) | 41 (47.7) |
| Age at MRI, yr | 36.5 ± 10.4 [18–63] | 37.3 ± 11.22 [19–66] |
| Right-handedness | 110 (96.5) | 84 (97.7) |
| IQ* | 108.7 ± 10.58 | 107.39 ± 10.06 |
| Medication | ||
| Lithium | 39 (33.3) | — |
| Anticonvulsants | 64 (54.7) | — |
| Antipsychotic | 52 (44.4) | — |
| Antidepressant | 54 (46.2) | — |
| Age at onset, yr | 20.8 ± 8.0 | — |
| YMRS score†‡§ | 2.6 ± 3.7 | — |
| MADRS score†§ | 3.5 ± 5.4 | — |
| HAMD-17 score‡ | 9.9 ± 7.9 | — |
BD = bipolar disorder; HAMD-17= Hamilton Rating Scale for Depression; NART = National Adult Reading Test; MADRS = Montgomery–Asberg Depression Rating Scale; SD = standard deviation; YMRS = Young Mania Rating Scale.
*
Assessed using the NART.
†
Recorded at centre 1.
‡
Recorded at centre 2.
§
Recorded at centre 3.