Table 3.
Region of Interest |
Hemi- sphere |
F | FDR q- value |
Effect Size |
↑ or ↓ in 22q11DS -ASD+ vs. 22q11DS -ASD- |
↑ or ↓ in 22q11DS -ASD+ vs. CTL |
↑ or ↓ in 22q11DS -ASD- VS. CTL |
---|---|---|---|---|---|---|---|
Cerebellum (white matter) |
L | 26.1 | 0.000000009 | 0.32 | ↓ | ↓ | |
R | 26.3 | 0.000000009 | 0.33 | ↓ | ↓ | ||
Cerebellum (cortex) |
L | 18.0 | 0.000002 | 0.25 | ↓ | ↓ | |
R | 17.6 | 0.000002 | 0.24 | ↓ | ↓ | ||
Caudate | L | 4.8 | 0.02 | 0.08 | ↑ | ↑ | |
R | 7.2 | 0.003 | 0.11 | ↑ | ↑ | ||
Putamen | L | 2.4 | 0.13 | 0.04 | |||
R | 5.6 | 0.01 | 0.09 | ↓ | ↓ | ||
Hippocampus | L | 4.6 | 0.02 | 0.08 | ↓ | ||
R | 12.3 | 0.0001 | 0.18 | ↓ | ↓ | ||
Amygdala | L | 4.7 | 0.02 | 0.08 | ↓ | ↓ | |
R | 7.0 | 0.003 | 0.11 | ↓ | ↓ | ||
Nucleus accumbens area |
L | 2.7 | 0.11 | 0.05 | |||
R | 11.4 | 0.0002 | 0.17 | ↑ | ↑ | ||
Ventral diencephalon |
L | 5.5 | 0.01 | 0.09 | ↓ | ↓ | |
R | 3.9 | 0.04 | 0.07 | ↓ | |||
Thalamus | L | 0.7 | 0.56 | 0.01 | |||
R | 0.9 | 0.45 | 0.01 | ||||
Pallidum | L | 2.7 | 0.11 | 0.05 | |||
R | 3.2 | 0.06 | 0.06 | ||||
Corpus callosum (posterior) |
N/A | 3.1 | 0.07 | 0.05 | |||
Corpus callosum (mid- posterior) |
N/A | 0.3 | 0.8 | 0.01 | |||
Corpus callosum (central) |
N/A | 1.1 | 0.4 | 0.02 | |||
Corpus callosum (mid- anterior) |
N/A | 0.3 | 0.7 | 0.01 | |||
Corpus callosum (anterior) |
N/A | 11.2 | 0.0002 | ↑ | ↑ |
↓ or ↑ indicates measures that showed a statistical significance in the results (p-values <.05).