Table 1.
Type I error rates for standard and robust EB t-tests. Datasets were simulated with different d0 values but with no DE genes and or outliers. The table gives the mean error rate over all genes in 1,000 simulated datasets for various p-value cutoffs.
d0 | Method | Nominal error rate
|
|||
---|---|---|---|---|---|
0.001 | 0.01 | 0.05 | 0.1 | ||
2 | Standard | 0.000996 | 0.00998 | 0.05001 | 0.09994 |
Robust | 0.000996 | 0.00998 | 0.04996 | 0.09983 | |
4 | Standard | 0.001008 | 0.01002 | 0.05008 | 0.10012 |
Robust | 0.001013 | 0.01004 | 0.05006 | 0.10005 | |
10 | Standard | 0.001017 | 0.01005 | 0.05018 | 0.10008 |
Robust | 0.001033 | 0.01010 | 0.05021 | 0.10005 |