Table 2.

Main results of significant SNPs at 20p11.

				FHS (N=6004)		KCOS (N=2207)		OOS (N=968)		Meta (N=9179)
rs#	Position	Alleles	EAF	beta	p	beta	p	beta	p	beta	p	I2 (%)
rs910983	19738164	C/T	0.36	−0.11	1.00×10−6	−0.07	0.02	−0.12	0.02	−0.10	4.94×10−9	0.0
rs111678496	19744988	M/W	0.64	0.11	4.25×10−7	0.07	0.02	0.12	0.02	0.10	2.08×10−9	0.0
rs16981092	19745011	A/G	0.64	0.11	6.18×10−7	0.07	0.03	0.12	0.01	0.10	3.49×10−9	0.0
rs6112563	19745561	C/T	0.36	−0.11	5.94×10−7	−0.07	0.03	−0.12	0.02	−0.10	3.35×10−9	0.0
rs6112565	19748442	A/G	0.68	0.11	4.04×10−7	0.09	0.01	0.10	0.07	0.10	1.84×10−9	0.0
rs2069126	19749957	A/G	0.36	−0.11	3.26×10−7	−0.07	0.03	−0.12	0.02	−0.10	1.82×10−9	0.0
rs78194863	19751524	C/G	0.76	0.12	4.52×10−8	0.05	0.14	0.07	0.21	0.10	2.99×10−8	30.3
rs6046308	19755673	G/T	0.26	−0.12	1.95×10−8	−0.05	0.17	−0.04	0.38	−0.09	3.74×10−8	49.1
rs6046310	19757284	A/G	0.74	0.13	6.22×10−9	0.05	0.15	0.06	0.27	0.10	8.03×10−9	47.5
rs12481515	19777184	C/T	0.84	0.14	5.87×10−8	0.08	0.05	0.03	0.66	0.11	4.48×10−8	40.7

Notes: The first and second alleles represent the effect and alternative alleles. EAF was the effect allele frequency. rs111678496 is an DIV, where "M" and "W" represent mutant (TGCTAGTCAGAT) and wild (-) alleles, respectively. Beta is the regression coefficient of normalized phenotypic residual on the effect allele.GWS significant p-values were marked in bold.