Table 2. Transition Probabilities between Subgroups.

Subgroup	1 Low Symptom Burden	2 Mild Fatigue	3 Mild Fatigue & Mild Pain	4 Moderate Fatigue & Moderate Pain	5 Moderate Fatigue & Moderate Psych	6 Moderate Fatigue & Mild Pain & Psych	7 High Symptom Burden
1 Low Symptom Burden	0.88 (U)	0.01 (W)	0.08 (W)	0.02 (W)	0.00 (W)	0.00 (W)	0.00 (W)
2 Mild Fatigue	0.08 (I)	0.73 (U)	0.12 (N)	0.00 (W)	0.01 (W)	0.06 (W)	0.00 (W)
3 Mild Fatigue & Mild Pain	0.10 (I)	0.03 (N)	0.72 (U)	0.11 (W)	0.00 (W)	0.03 (W)	0.01 (W)
4 Moderate Fatigue & Moderate Pain	0.04 (I)	0.07 (I)	0.28 (I)	0.53 (U)	0.00 (N)	0.07 (N)	0.01 (W)
5 Moderate Pain & Moderate Psychological	0.00 (I)	0.09 (I)	0.00 (I)	0.04 (N)	0.59 (U)	0.07 (N)	0.20 (W)
6 Moderate Fatigue & Mild Pain & Psychological	0.00 (I)	0.08 (I)	0.07 (I)	0.09 (N)	0.00 (N)	0.65 (U)	0.10 (W)
7 High Symptom Burden	0.00 (I)	0.01 (I)	0.01 (I)	0.03 (I)	0.12 (I)	0.16 (I)	0.67 (U)

U = unchanged or no transition; I = improved; W = worsened; N = not classified. Transition probabilities for each subgroup dyad are estimated under model assumption of uniform probability of transitioning from one timepoint to next consecutive time point. Each entry represents the probability of transitioning from the subgroup indicated by the row to the subgroup indicated by the column. Therefore, all entries in a row sum to 1.0.