Table 2.
GEE Modeling of Stimulated Parotid Salivary Flow Rate with Time – Treated Gland
| Time | SPFR | 95% CI | Robust SE | p-value |
|---|---|---|---|---|
|
| ||||
| Model 1a | ||||
| Visit 2 | 0.142 | 0.102, 0.182 | 0.020 | <0.001* |
| Visit 3 | −0.008 | −0.043, 0.026 | 0.018 | 0.632 |
| Visit 4 | 0.087 | 0.000, 0.175 | 0.045 | 0.051 |
| Visit 5 | 0.145 | −0.008, 0.298 | 0.078 | 0.063 |
| Visit 6 | 0.177 | 0.062, 0.291 | 0.058 | 0.002* |
| Visit 7 | 0.152 | −0.007, 0.311 | 0.081 | 0.061 |
| Visit 8 | 0.131 | 0.093, 0.169 | 0.019 | <0.001* |
| Visit 9 | 0.114 | 0.039, 0.189 | 0.038 | 0.003* |
| Visit 10 | 0.099 | 0.048, 0.151 | 0.026 | <0.001* |
| Visit 11 | 0.176 | 0.113, 0.239 | 0.032 | <0.001* |
| Visit 12 | 0.146 | 0.038, 0.254 | 0.055 | 0.008* |
| Visit 13 | 0.207 | 0.031, 0.384 | 0.090 | 0.021* |
| Visit 14 | 0.184 | 0.098, 0.270 | 0.044 | <0.001* |
| Visit 15 (follow-up 1) | 0.166 | 0.055, 0.277 | 0.057 | 0.003* |
| Visit 16 (follow-up 2) | 0.269 | 0.140, 0.397 | 0.066 | <0.001* |
|
| ||||
| Model 1b | ||||
|
| ||||
| Time | 0.009 | 0.005, 0.013 | 0.002 | <0.001* |
|
| ||||
| Model 2a | ||||
|
| ||||
| Peak 1 | 0.262 | 0.130, 0.395 | 0.068 | <0.001* |
| Follow-up 1 | 0.153 | 0.041, 0.265 | 0.057 | 0.007* |
| Follow-up 2 | 0.255 | 0.128, 0.382 | 0.065 | <0.001* |
|
| ||||
| Model 2b | ||||
|
| ||||
| Time | 0.049 | 0.006, 0.091 | 0.022 | 0.025* |
SPFR: Stimulated parotid salivary flow rate. Model 1a - all 16 visits in the model with visits treated as a categorical time variable. Visit 1 is the reference (baseline). Model 1b - all 16 visits in the model with visits treated as continuous time variable. Model 2a - 4 visits (stimulated parotid salivary flow rate at peak 1, follow-up 1 and follow-up 2 visits were compared to baseline flow rates) in the model with visits treated as categorical time variable. Visit 1 is the reference (baseline). Model 2b - 4 visits in the model with visits treated as continuous time variable. Estimates are rounded to three decimal places.
*
Statistically significant.