Table 2.
The isometric force at which the indicated protein oscillates between folded and unfolded states.
| Protein domain | Isometric force pN | Method | ref |
|---|---|---|---|
| RNase H (molten glob -> unfold) | 5.5 | optical tw | Cecconi…Marqusee 2005 [22] |
| apomyoglobin (molten glob -> unfold) | 4.5 | optical tw | Elms…Marqusee 2012 [23] |
| titin I27 | 5.4 | magnetic tw | Chen…Yan 2015 *[24] |
| barnase | 4.0 | optical tw | Alemany…Ritort 2016 [25] |
| NuG2 | 8.5 | AFM | He…Li 2015 [26] |
| calmodulin | 6 (folding) 12 (unfolding) | AFM | Junker…Rief 2009 [27] |
| calmodulin | 10.5 | optical tw | Stigler…Rief 2011 [28] |
| villin HP35 | 7 for wt; 10 for stabilized mutant | optical tw | Zoldak…Rief 2013 [29] |