Table 1.
Clinical (% or N [%]) and biochemical (median [25th, 75th percentiles]) variables among women with discordant or concordant values of nonHDL-c and apoB.
| Discordant | Concordant | Discordant | |
|---|---|---|---|
| apoB Lower Than Expected (Low Negative Residual) (n=6,884) | apoB Close to Expected (Intermediate Residual) (n=13,765) | apoB Higher Than Expected (High Positive Residual) (n=6,884) | |
| Age, years | 51.9 (48.2, 57.5) | 52.7 (48.9, 58.6) | 54.7 (50.1, 61.0) |
| Family history premature MI*, % | 13.3 | 14.3 | 15.7 |
| Smoker**, % | 47.3 | 48.0 | 49.9 |
| Post-menopausal, % | 48.9 | 52.9 | 62.6 |
| HRT use, % | 36.5 | 41.9 | 50.1 |
| Cardiometabolic Traits | |||
| Metabolic syndrome, % | 16.5 | 21.1 | 40.0 |
| BMI, kg/m2 | 24.2 (22.0, 27.4) | 24.8 (22.3, 28.3) | 25.8 (23.2, 29.6) |
| Hypertension, % | 20.8 | 23.2 | 33.3 |
| Diabetes, % | 2.0 | 2.1 | 4.7 |
| hsCRP, mg/L | 1.57 (0.62, 3.59) | 1.89 (0.76, 4.07) | 2.84 (1.28, 5.51) |
| Triglycerides, mg/dL | 109 (77, 162) | 110 (79, 158) | 154 (108.5, 217.0) |
| Lipid/Lipoprotein Profile | |||
| HDL-c, mg/dL | 57.7 (48.2, 68.8) | 52.6 (44.3, 62.4) | 45.2 (37.7, 54.2) |
| LDL-c, mg/dL | 116.2 (94.0, 142.9) | 118.1 (99.6, 139.2) | 132.3 (112.2, 154.3) |
| nonHDL-c, mg/dL | 149.0 (123.3, 182.4) | 148.2 (126.5, 173.8) | 170.6 (147.8, 195.9) |
| apoB, mg/dL | 83.7 (70.2, 97.9) | 97.5 (84.9, 114.0) | 126.9 (112.8, 143.4) |
| LDL size, nm | 21.3 (20.9, 21.6) | 21.2 (20.8, 21.6) | 20.9 (20.3, 21.3) |
| LDL-p, μmol/L | 1,030 (832, 1,263) | 1,178 (975, 1,409) | 1,527 (1,280, 1,800) |
| VLDL-p, μmol/L | 54 (40, 73) | 57 (41, 75) | 68 (49, 87) |
Abbreviations: CABG = coronary artery byupass grafting, hsCRP = high sensitivity C-reactive protein, HbA1c = glycated hemoglobin A1c, HRT = hormone replacement therapy, LDLp = low density lipoprotein particle concentration, MI = myocardial infarction, nm = nanometer, PTCA = percutaneous transluminal coronary angioplasty.
*
Family history premature MI <60 years of age.
**
Current or Former.
To convert mg/dL to mmol/L multiply by 0.02586 for cholesterol and by 0.01129 for triglycerides.