Table 3.

Multiple linear regression models of fatigue and cognitive function in SLE patients

	Unadjusted			Age adjusted			Fully adjusteda
	B	SE B	p value	B	SE B	p value	B	SE B	p value
Fatigue
BMI (kg/m2)	0.093	0.034	0.01	0.106	0.033	0.003	0.102	0.033	0.004
Anxiety	0.132	0.041	0.003	0.119	0.044	0.01	0.127	0.044	0.006
Depression	0.175	0.046	0.0004	0.162	0.048	0.001	0.170	0.047	0.001
MD (10−6 mm2/s)	−0.580	0.234	0.02	−0.556	0.249	0.03	−0.610	0.253	0.02
IFN (RQ value)	−0.090	0.030	0.006	−0.091	0.029	0.005	−0.080	0.040	0.06
vWF (fVIIIc) (IU/mL)	−1.168	0.550	0.04	−1.121	0.539	0.04	−1.111	0.533	0.04
vWF (RCOF) (IU/mL)	−1.426	0.599	0.02	−1.212	0.623	0.06	−1.154	0.616	0.07
Cognitive function
Disease duration (months)	−0.003	0.001	0.003	−0.003	0.001	0.005	−0.001	0.000	0.07
MD (10−6 mm2/s)	−0.271	0.126	0.04	−0.264	0.135	0.06	−0.012	0.108	0.91
vWF (Ag) (IU/mL)	−0.800	0.204	0.0003	−0.794	0.215	0.0006	−0.286	0.208	0.18
vWF (RCOF) (IU/mL)	−0.889	0.358	0.02	−0.848	0.380	0.03	−0.296	0.317	0.36
IL-6 (pg/mL)	−0.234	0.080	0.006	−0.241	0.080	0.005	−0.151	0.063	0.02

^aFatigue adjusted for age, disease duration and seroids; Cognitive function adusted for age, disease duration, steroids and NART.

B = beta coefficient, IL-6 = interleukin-6, MD = mean difussivity, NART = national adult reading test, SE B = standard error for beta coefficient, vWF Ag = von Willebrand Factor antigen, vWF fVIIIc = von Willebrand Factor VIII, vWF RCOF = von Willebrand Factor ristocen co-factor