Table 1.
Model parameters and corresponding cell currents in the model of the guinea pig left ventricular cardiomyocyte, as well as the perturbation factors used in the dynamic clamp experiments
| Parameter | Current | Dynamic clamp scaling |
|---|---|---|
| G Kr | Rapid delayed rectifier K+ current (I Kr) | –40% |
| G Ks | Slow delayed rectifier K+ current (I Ks) | +40% |
| G K1 | Inward rectifier K+ current (I K1) | –40% |
| G CaL | L‐type Ca2+ current (I CaL) | +40% |
| G CaT | T‐type Ca2+ current (I CaT) | –40% |
| G NaK | Na+/K+ ATPase current (I NaK) | +40% |
| G NCX | Na+/Ca2+ exchanger current (I NCX) | –40% |
| G Na | Fast Na+ current (I Na) | |
| G Nab | Background Na+ current (I Nab) | |
| G Cab | Background Ca2+ current (I Cab) | |
| G Kp | Plateau K+ current (I Kp) | |
| G pCa | Plasma Ca2+ ATPase current (I pCa) | |
| v SERCA | Sarco/endoplasmic reticulum Ca2+ ATPase |