Table 2.
Adjusted hazard ratios for mortality in patients after their 1st-ever mechanical ventilation n (%)
| No. of deaths | LC[Pos] patients (n = 5551) | LC[Neg] patients (n = 11102) | Adjusted hazard ratio (95%CI) |
| Overall | 3747 (67.50) | 5902 (53.16) | 1.38 (1.32-1.44)a |
| Age (yr) | |||
| < 50 | 763 (13.75) | 744 (6.70) | 1.96 (1.76-2.18)a |
| 50-64 | 911 (16.41) | 1369 (12.33) | 1.40 (1.29-1.53)a |
| 65-79 | 1368 (24.64) | 2458 (22.14) | 1.24 (1.16-1.32)a |
| ≥ 80 | 705 (12.70) | 1331 (11.99) | 1.41 (1.04-1.25)a |
| Gender | |||
| Male | 2464 (44.39) | 3770 (33.96) | 1.42 (1.35-1.49)a |
| Female | 1283 (23.11) | 2132 (19.20) | 1.30 (1.21-1.39)a |
| Department | |||
| Surgical | 255 (4.59) | 595 (5.36) | 1.32 (1.14-1.54)a |
| Medical | 3492 (62.91) | 5307 (47.80) | 1.37 (1.31-1.43)a |
| Number of organ failures | |||
| 0 | 2074 (37.36) | 4015 (36.16) | 1.40 (1.33-1.47)a |
| 1 | 1379 (24.84) | 1691 (15.23) | 1.26 (1.17-1.35)a |
| ≥ 2 | 294 (5.30) | 196 (1.77) | 1.16 (0.96-1.41) |
| Comorbidity | |||
| DM | 1374 (24.75) | 2432 (21.91) | 1.19 (1.12-1.28)a |
| HTN | 1583 (28.52) | 2851 (25.68) | 1.15 (1.08-1.22)a |
| CAD | 716 (12.90) | 1276 (11.49) | 1.17 (1.07-1.28)a |
| ESRD | 488 (8.79) | 920 (8.29) | 1.19 (1.06-1.33)a |
| COPD | 789 (14.21) | 1459 (13.14) | 1.15 (1.05-1.26)a |
| Cancer | 972 (17.51) | 1668 (15.02) | 1.31 (1.21-1.42)a |
| Stroke | 680 (12.25) | 1261 (11.36) | 1.16 (1.06-1.28)a |
| CHF | 563 (10.14) | 1002 (9.03) | 1.21 (1.09-1.34)a |
| HBV | 7 (0.13) | 12 (0.11) | 0.54 (0.11-2.57) |
| HCV | 11 (0.20) | 20 (0.18) | 0.43 (0.14-1.28) |
The model was adjusted for age, gender, length of hospital stay, length of 1st mechanical ventilation, length of intensive care unit stay, treatment department, number of organ failures, and the listed comorbidities.
a
P < 0.05. LC[Pos]: Liver cirrhosis-positive; LC[Neg]: Liver cirrhosis-negative; DM: Diabetes mellitus; HTN: Hypertension; CAD: Cardiovascular disease; ESRD: End-stage renal disease; COPD: Chronic obstructive pulmonary disease; CHF: Congestive heart failure; HBV: Hepatitis B virus; HCV: Hepatitis C virus.