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. 2017 Mar 31;7:103. doi: 10.3389/fcimb.2017.00103

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Copyright © 2017 Lu, Chen, Chiang, Wang, Hsiao, Huang, Lin, Cheng, Liang and Lai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immunohistochemical analysis of MMP-9 and LCN-2 expression in the brain upon K. pneumoniae 1084S infections. Representative images of brain sections retrieved from the control mice (A,G), the ΔClbA-inoculated mice (B,H), and the 1084-inoculated mice which developed meningitis (C–F) at the 7th day post-orogastric-inoculation are shown. Brown staining (arrows) indicates a positive reaction with the respective antibody against MMP-9 (A–E) and LCN-2 (F–H). Scale bar: 50 μm.