Table 1.
Clinicopathologic characteristics of patients undergoing neoadjuvant chemoradiotherapy (nCRT) and surgery for rectal cancer
Factors | Patients (n = 79) n (%) |
---|---|
Sex | |
Female | 23 (29) |
Male | 56 (71) |
Age (years) | |
<65 | 36 (46) |
65–74 | 34 (43) |
>75 | 9 (11) |
T-stage | |
0 (complete pathologic response) | 3 (4) |
1 | 4 (5) |
2 | 13 (16) |
3 | 47 (60) |
4 | 12 (15) |
N-stage | |
0 | 50 (63) |
1 | 14 (18) |
2 | 15 (19) |
M-stage | |
0 | 75 (95) |
1 | 4 (5) |
TNM stage | |
0 | 3 (4) |
1 | 13 (16) |
2 | 33 (42) |
3 | 26 (33) |
4 | 4 (5) |
Differentiation | |
Moderately/well | 68 (86) |
Poor | 10 (13) |
Unknown | 1 (1) |
Vascular invasion | |
No | 48 (61) |
Yes | 30 (38) |
Unknown | 1 (1) |
Perineural invasion | |
No | 67 (85) |
Yes | 9 (11) |
Unknown | 3 (4) |
Resection margin | |
Not involved | 65 (82) |
Involved | 14 (18) |
Neoadjuvant chemotherapy regimen | |
Capecitabine | 27 (34) |
5-FU | 44 (56) |
Other | 8 (10) |
Surgical procedure | |
Anterior resection | 38 (48) |
Abdominoperineal resection | 30 (38) |
Hartmann’s resection | 2 (3) |
Unknown | 9 (11) |
Radiologic response | |
Good response | 37 (47) |
No response | 30 (38) |
Disease progression | 12 (15) |
Pathologic response | |
No response | 44 (56) |
Good response | 35 (44) |
TNM tumor-node-metastasis, 5-FU 5-fluorouracil