Table 6.

Overlap of NeuroD PPI sets with HTT interactome_1619.

Gene ID	Symbol|Disease	n PPI	n common HTT PPI	FDR	% Set NeuroD
PD Set		763	370	5.4E-224	48
6622	SNCA	398	235	9.7E-165	59
120892	LRRK2	198	108	3.2E-69	55
11315	PARK7	147	73	6.0E-43	50
5071	PARK2	176	77	2.7E-40	44
65018	PINK1	52	25	1.2E-14	48
AD Set		2354	400	1.1E-65	17
4137	MAPT	118	67	2.2E-44	57
5663|5664	PSEN1|2	253	97	1.2E-44	38
351	APP	2133	310	3.3E-35	15
PolyQ Set		1139	303	2.1E-96	27
773	CACNA1A|SCA6	215	87	3.1E-42	40
4287	ATXN3|SCA3	98	44	1.0E-23	45
6311	ATXN2|SCA2	51	21	7.6E-11	41
6310	ATXN1|SCA1	272	74	2.7E-23	27
367	AR|SBMA	325	86	4.3E-26	26
6908	TBP|SCA17	246	57	1.0E-14	23
6314	ATXN7|SCA7	87	23	1.5E-07	26
1822	ATN1|DRPLA	115	28	3.7E-08	24
ALS Set		328	123	1.7E-55	38
6647	SOD1	84	36	1.0E-18	43
23435	TARDBP	120	46	2.5E-21	38
2521	FUS	159	54	5.0E-22	34
SMA 6606|6607	SMN1|2	241	67	1.10E-21	28